Blueprint Neurotherapeutics Network
How BPN Works: The Virtual Pharma Model
Successful applicants to the BPN receive funding for activities to be conducted in their own laboratories, no-cost access to contracted drug discovery and development services, no-cost access to drug discovery and development consultants, and they retain intellectual property rights for drug candidates developed through the BPN program.
The Lead Development Team (LDT) is highly collaborative in nature and is the cornerstone of the BPN’s infrastructure. The Principal Investigator and a Lead Consultant co-chair the LDT. The PI’s research team works closely with highly experienced consultants and BPN Staff, holding bi-weekly teleconferences to propose project milestones, design experiments, and review data. Decisions are made by consensus, within budgetary constraints.
Drug discovery and development services are offered through NIH-funded Contract Research Organizations (CROs) specializing in medicinal chemistry, ADME, toxicology, formulations development, GMP synthesis to enable IND-filing, and Phase I clinical testing. A UG3/UH3 or U44 grant award is provided to fund studies conducted by the Principal Investigator and associated personnel.