The Allen Institute for Brain Science (Seattle, Washington) is under contract to conduct a high throughput analysis of gene
expression in the developing Rhesus macaque brain.
The goal is to produce a publicly accessible gene expression map of the macaque brain, and to lay the groundwork for mapping
gene expression in the human brain.
Under a subcontract, the University of California Davis will collect and prepare Rhesus macaque brain tissue for gene expression
analysis.
In partnership with the UC Davis/NINDS/NIMH NeuroMab Facility, this initiative is funding the targeted manufacture and distribution of a large number of high quality monoclonal antibodies
for neurodevelopment research.
A list of antibody targets in progress can be found at www.neuromab.org under Current Projects.
Understanding how neural circuits take shape is essential for understanding how the normal brain functions and how abnormal
brain development contributes to neurological and mental health disorders.
This RFA solicited novel approaches for the study and manipulation of neural circuits as they form during development.